|
KMID : 1009020220200030573
|
|
Clinical Psychopharmacology and Neuroscience
2022 Volume.20 No. 3 p.573 ~ p.577
|
|
|
The Cumulative Effect of Antipsychotic Usage on Mortality in Schizophrenia: A Nationwide Population-based Cohort Study in Korea
|
|
Kim Gyu-Rin
Rim Soo-Jung
Jo Min-Kyung
Lee Min-Geu
Park Se-Jin
Park Su-Bin
|
|
|
Abstract
|
|
|
Objective: To investigate the cumulative effect of antipsychotics at different dosages on mortality in patients with schizophrenia.
Methods: We analyzed data from the Korean National Health Insurance System?National Sample Cohort covering the 2002?2013 period. We used Cox regression analysis to calculate hazard ratios for mortality risks according to cumulative antipsychotic exposure levels (low, moderate, and high).
Results: Our analyses revealed no significant association between antipsychotic exposure and mortality (either all-cause or cause-specific) in patients with schizophrenia.
Conclusion: Our results imply that the excess mortality of patients with schizophrenia is attributable to factors other than antipsychotic usage.
|
|
|
KEYWORD
|
|
|
Schizophrenia, Antipsychotics, Mortality, South Korea
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
  
|